Catalog No.
Product Name
Application
Product Information
Citations
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Fluorescent Dye
C.I. Pigment Orange 36 is a fluorescent dye primarily utilized for its robust coloring properties across various applications. It exhibits excellent stability and chemical resistance, making it suitable for use in textiles, cosmetics, plastics, inks, and more. This compound is valuable in research focused on colorimetric assays, dye-sensitized solar cells, and developing formulations in the pharmaceutical and food industries. -
Fluorescent Dye
C.I. Pigment Orange 38 is a fluorescent dye that exhibits high stability across various media, making it an essential colorant for numerous applications. Its robust color properties allow for effective use in diverse industries, including textiles, cosmetics, food, and plastics. This compound facilitates color enhancement in formulations such as paints, inks, photography materials, and paper products, supporting a wide range of research and industrial applications. -
Fluorescent Dye
C.I. Acid Yellow 49 is a fluorescent dye known for its ability to selectively absorb onto various surfaces. This compound exhibits high stability and solubility in aqueous environments, making it suitable for various biological and chemical applications. It is commonly utilized in fluorescence microscopy, staining protocols, and in assays requiring detection through fluorescence. Its unique properties allow for enhanced visualization and tracking of biological samples in research settings. -
Fluorescent Dye
C.I. Pigment Yellow 62 is a fluorescent dye known for its stability and resistance to chemical alteration in various media. This compound exhibits excellent colorant properties and is utilized across diverse applications, including textiles, pharmaceuticals, food products, cosmetics, plastics, paints, inks, photography, and paper manufacturing. Its robust performance makes it an essential reagent in color development and enhancement for multiple industrial sectors. -
Lymphatic Dye
Isosulfan blue is a lymphatic dye primarily used for the visualization of lymphatic vessels during lymphangiography. It is particularly instrumental in sentinel lymph node biopsies, especially in the context of breast cancer surgery. While effective in identifying lymphatic pathways, it is important to note that allergic reactions may occur during its use in clinical applications. -
Fluorescent Dye
Calcein (tetraethyl ester) is a fluorescent dye that permeates cellular membranes, enabling its use in live cell imaging. This compound is widely utilized for assessing cell viability and for short-term labeling applications in biological research. Its strong fluorescence allows for effective visualization of cellular processes in various experimental contexts. -
DNA-binding Dye
Propidium monoazide (PMA) is a cell-impermeant photoreactive DNA-binding dye that selectively targets double-stranded DNA (dsDNA). It effectively prevents the amplification of DNA derived from dead bacteria during polymerase chain reaction (PCR), enhancing both the specificity and sensitivity of PCR assays. Additionally, PMA serves as a click chemistry reagent, containing an azide group that participates in copper-catalyzed azide-alkyne cycloaddition (CuAAc) and strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with alkyne-containing molecules, DBCO, or BCN groups, facilitating advanced chemical labeling and analysis in research applications. -
H2O2 Dye
FBBBE is a selective fluorescent dye for the detection of hydrogen peroxide (H2O2) within cells. Upon exposure to intracellular H2O2, FBBBE undergoes a chemical transformation to fluorescein, leading to enhanced intracellular fluorescence (Ex=480 nm, Em=512 nm). This compound is valuable in studies examining oxidative stress and cellular responses to reactive oxygen species. -
Fluorescent Dye
5(6)-Carboxynaphthofluorescein is a pH-sensitive fluorophore known for its ability to fluoresce within an alkaline pH range. This compound serves as an effective fluorescent pH indicator, with excitation and emission wavelengths of 593 nm and 668 nm, respectively. It is particularly useful in the development of fiber-optic pH sensors and various biological and chemical research applications that require real-time pH monitoring. -
Sphingomyelinase Fluorescent Substrate
C12 NBD Sphingomyelin serves as a substrate for sphingomyelinase, incorporating a fluorescent C12 nitrobenzoxadiazole tag. This reagent enables the study of sphingomyelin metabolism and transport under fluorescence microscopy or spectroscopy, with an excitation wavelength of 470 nm and emission at 525 nm. Its application is critical for researchers investigating sphingolipid dynamics and related cellular processes. -
Ca2+ Fluorescent Indicator
Fura-2 pentapotassium is a cell-impermeable fluorescent dye designed for intracellular calcium imaging, targeting Ca2+ ions. It exhibits an emission wavelength of 510 nm, with excitation wavelengths at 340 nm and 380 nm. The fluorescence intensity ratio of 340 nm to 380 nm is directly proportional to intracellular Ca2+ levels, making it a valuable tool for studies related to calcium signaling and cellular physiology. -
Fluorescent Dye
Meldola blue is a fluorescent dye primarily used as a biosensor for measuring lactate levels in serum. This reagent is designed for application on screen-printed carbon electrodes modified with Meldola's Blue-Reinecke salt (MBRS-SPCE) and incorporates the lactate dehydrogenase NAD+-dependent enzyme derived from pig heart, in conjunction with NAD+. It facilitates sensitive detection of lactate, making it valuable for research in metabolic studies and clinical diagnostics. -
Fluorescent Probe
(±)-ANAP hydrochloride is an unnatural amino acid analog of prodan that functions as a fluorescent probe, enhancing the sensitivity to environmental changes. Its unique fluorescent properties make it valuable for studying protein conformational dynamics and interactions in various biological systems. This reagent is commonly utilized in fluorescence spectroscopy and microscopy applications to monitor changes in cellular environments. -
Endoplasmic Reticulum Fluorescent Probe
AIE-ER is an advanced fluorescent probe designed for targeting the endoplasmic reticulum (ER), functioning through the aggregation-induced emission (AIE) mechanism. This probe displays exceptional photostability and high brightness, making it suitable for sensitive imaging applications. AIE-ER enables researchers to investigate ER-related pathologies, providing insights into cellular processes and disease mechanisms associated with ER dysfunction. -
Fluorescent Cholesterol Analog
3-C12-NBD-cholesterol is a fluorescent cholesterol analog that targets cellular membranes to facilitate the study of cholesterol trafficking dynamics. This compound allows for real-time visualization and quantification of membrane and intracellular cholesterol distribution in various biological systems. It is an essential tool for investigating membrane biology, lipid metabolism, and the role of cholesterol in cellular processes. -
Fluorescent Dyes
Resorufin acetate is a fluorescent dye that selectively targets hydrazine, enabling sensitive detection in various biological samples. This compound exhibits strong fluorescence upon reduction, making it a valuable tool in research applications focused on environmental monitoring, biochemical assays, and the study of oxidative stress. Its utility in detecting hydrazine enhances analytical capabilities in both research and laboratory settings. -
Fluorescent Labeling Reagent
9-Anthryldiazomethane is a fluorescent labeling reagent that selectively targets fatty acids and their derivatives for detection. This compound enables sensitive fluorescence-based assays, facilitating the study of lipid metabolism and related biological processes. Its application in fluorescent labeling makes it a valuable tool in biochemical research. -
pH Fluorescent Probe
2',7'-Difluorofluorescein is a pH-sensitive fluorescent probe with a pKa of approximately 4.7. It provides ratiometric pH analysis through altered fluorescence intensity upon excitation at 488 nm, facilitating quantitative pH measurements between 2 and 7, particularly in submicron aerosol particles. This compound is notable for its ability to undergo buffer-mediated excited-state proton transfer and maintain stable fluorescence characteristics in physiological pH ranges, making it suitable for applications in fluorescent imaging, calcium indicator systems, and as a fluorescent protein label. Additionally, it demonstrates resistance to photodegradation, ensuring reliability in experimental settings. -
Oligomer-Specific Fluorescent Chemical Probe
BD-Oligo is an oligomer-specific fluorescent chemical probe that selectively targets Aβ oligomer assemblies, distinguishing them from monomers and fibrils. Utilizing diversity-directed fluorescent library screening and advanced computational techniques, BD-Oligo enables real-time monitoring of oligomer formation during Aβ peptide fibrillogenesis. Additionally, this probe demonstrates blood-brain barrier permeability, allowing for in vivo staining of Aβ oligomers, making it a valuable tool for studying Alzheimer's disease and related neurodegenerative processes. -
Cell Membrane Fluorescent Dye
FM1-84 is a cell membrane fluorescent dye that serves as a valuable tool for visualizing synaptic vesicle recycling in neurons. Its lipophilic properties enable effective membrane association, enhancing fluorescence intensity with excitation at 510 nm and emission at 625 nm. This compound is essential for studies focusing on neuronal activity, membrane dynamics, and synaptic processes. -
Mg2+ Fluorescent Probe
KMG-301AM is an acetoxymethyl ester of KMG-301 designed as a Mg2+ fluorescent probe targeting mitochondria. Upon accumulation within mitochondria, KMG-301AM is hydrolyzed to the active form, KMG-301, which is selective for Mg2+ detection in intact cells. This compound remains retained in the mitochondria due to the impermeable nature of the mitochondrial membrane, allowing it to reliably indicate variations in mitochondrial Mg2+ concentration and facilitate studies of Mg2+ transport across the mitochondrial membrane in cellular models. -
Fluorescent Probe
H2S Fluorescent Probe 1 is a selective fluorescent probe designed for the detection of hydrogen sulfide (H2S) in biological systems. This compound exhibits minimal cytotoxicity, making it suitable for use in live-cell imaging. Upon interaction with increased concentrations of hydrogen sulfide, H2S Fluorescent Probe 1 demonstrates a pronounced absorption peak at 485 nm, and fluorescence intensity at 434 nm sharply increases. This high sensitivity enables various research applications, including studies on cellular signaling and oxidative stress responses. -
Fluorescent Dye
5-HMSiR-Hoechst is a fluorescent dye designed for DNA probing, combining the characteristics of Hoechst 33258 with spontaneously blinking far-red hydroxymethyl silicon-rhodamine (HMSiR). This reagent effectively stains living cells, allowing for comprehensive visual analysis of cellular structures. With an excitation/emission wavelength of 640 nm/675 nm, it is suitable for advanced fluorescence imaging applications in various biological research studies. -
Calcium Indicator
Fura-FF pentapotassium is a low-affinity fluorescent dye designed for calcium detection. It exhibits distinctive fluorescence properties with excitation and emission wavelengths of 365/514 nm in the absence of calcium, shifting to 339/507 nm in the presence of high calcium concentrations. This dye is widely used in cellular and molecular biology research to study calcium dynamics and signaling pathways in live cells. -
ONOO⁻ Fluorescent Probe
DCM-ONOO is a near-infrared two-photon fluorescent probe targeting peroxynitrite (ONOO⁻) for real-time monitoring. This reagent features excellent optical properties, with a single photon excitation at 520 nm and emission at 685 nm, and a two-photon excitation at 820 nm. Upon interaction with ONOO⁻, DCM-ONOO exhibits a significant fluorescence shift from 460 nm to 512 nm, enabling specific detection of ONOO⁻ in biological samples. DCM-ONOO has been effectively utilized in rat models of epilepsy, offering insights into the dynamic fluctuations of peroxynitrite in neurological conditions. -
Dye
Mito Red is a vital dye that selectively accumulates in mitochondria, serving as a mitochondrial stain for evaluating mitochondrial function and status. Its fluorescence intensity is directly correlated with the mitochondrial membrane potential; an increase in membrane potential results in a corresponding increase in fluorescence signal. Mito Red is an essential tool for researchers studying mitochondrial activity, dysfunction, and related cellular processes. -
Dye
Bromopyrogallol Red is a multifunctional dye primarily used for biological research. It facilitates the observation and analysis of cell structures, tracking of biomolecules, and evaluation of cell functions. This compound serves diverse applications, including the differentiation of cell types, biomolecule detection, and tissue pathology studies. Additionally, it is utilized in various fields such as textile dyeing, food pigments, and emerging technologies like dye-sensitized solar cells. -
Dye
TOTO-3 is a multifunctional dye that serves as a vital tool in biological experiments. Its key biological activity includes the ability to visualize and differentiate cellular structures, track biomolecules, and assess cell functions. TOTO-3 is widely used in various research applications, including cell type differentiation, biomolecule detection, tissue pathology studies, and microbial monitoring. Additionally, this dye has potential uses in emerging fields such as functional textiles, food pigments, and dye-sensitized solar cells. -
Fluorescent Lipid
3-C6-NBD-cholesterol is a fluorescent analog of cholesterol that targets cellular membranes. This reagent is valuable for studying the dynamics of membrane and intracellular trafficking, enabling researchers to visualize and quantify lipid movement within biological systems. Its fluorescent properties make it an essential tool in lipid metabolism and membrane biology research applications. -
Calcium Fluorescent Probe
Calcium Green-5N AM is a potent Ca2+-sensitive fluorescent probe designed for monitoring intracellular calcium levels. Upon binding calcium ions (Ca2+), it exhibits a significant increase in fluorescence intensity, allowing for precise detection of free Ca2+ in neuronal cells. This probe is particularly valuable in studies of calcium signaling and neuronal activity. -
Fluorescent Chelating Indicator
BAPTA-TMFM is a fluorescent chelating indicator specifically designed to bind free calcium ions within the cytosol. It allows for the visualization and quantification of calcium fluctuations in live cells, thus providing valuable insights into calcium signaling pathways. This reagent is widely utilized in cellular and molecular biology research to investigate the role of calcium in various physiological and pathological processes. -
Red-Orange Fluorescent Dye
DiIC16(3) is a long-chain carbocyanine dye with red-orange fluorescence properties. This dye is frequently utilized for labeling a variety of biological entities, including cells, organelles, liposomes, viruses, and lipoproteins. Its high photostability and membrane affinity make it an essential tool in fluorescence microscopy and flow cytometry applications for studying cellular processes and interactions. -
Fluorescent Probe
Carboxy SNARF-1, acetoxymethyl ester (5/6-mixture) is a fluorescent probe that targets intracellular pH variations through pH-sensitive fluorescence. This compound enables the real-time measurement of intracellular pH changes, making it valuable for research applications in cell biology and physiology. Its versatility allows for use in various live cell imaging studies to monitor cellular processes influenced by pH. -
Pyridinium Dye
RH 414 is a styryl pyridinium dye that serves as a valuable tool for studying synaptic vesicle membrane trafficking. This compound enables real-time optical monitoring of vesicle dynamics, thereby facilitating research into synaptic function and neurotransmitter release processes. Its application is particularly beneficial for neuroscientific studies focusing on synaptic transmission and related cellular mechanisms. -
Fluorescent pH Indicator
OG 488, acid, is a fluorescent pH indicator commonly used in biochemical research and neurosciences. This compound exhibits pH-dependent fluorescence properties, allowing for precise monitoring of pH changes in biological environments. Its applications span various assays, including cellular imaging and biochemical analyses, making it a valuable tool for researchers studying pH dynamics in live cells. -
Fluorescent Dye
HOE-S 785026 trihydrochloride is a fluorescent dye primarily utilized as a live nuclear marker. It selectively binds to A/T-rich regions of double-stranded DNA, significantly enhancing fluorescence intensity, making it ideal for labeling living cells. This dye is applicable in various biological research contexts, including cell cycle studies and genetic analyses, with fluorescence responses positively correlating with increases in solution pH. -
Azo Dye
Alizarine Yellow R, a salicylic acid derivative and azo dye, functions primarily as a pH indicator. It exhibits key biological activity as a staining agent in various chemical examinations and is utilized in biological research. Additionally, Alizarine Yellow R finds applications in dyeing industries, making it a versatile reagent in both laboratory and industrial settings. -
Voltage-sensitive Fluorescent Dye
Oxonol 595 is a voltage-sensitive fluorescent dye that selectively indicates membrane potential changes in live cells. This compound exhibits significant fluorescence shifts in response to alterations in voltage, making it valuable for studying neuronal activity and membrane dynamics. Its applications include the investigation of excitability in various cell types and the analysis of membrane potential in cardiovascular research. -
Calcium Fluorescent Indicator
INDO 1 pentapotassium is a cell-impermeant fluorescent calcium indicator that specifically binds to Ca2+ ions, facilitating the detection of calcium levels within biological systems. Upon binding, the compound exhibits a significant fluorescence shift, with the maximum emission wavelength changing from 485 nm to 410 nm. This property makes INDO 1 pentapotassium a valuable tool for studying calcium signaling and dynamics in various research applications. -
Membrane Potential Fluorescence Dye
Di-2-ANEPEQ is a voltage-sensitive membrane potential fluorescence dye that exhibits significant changes in fluorescence intensity in response to alterations in membrane potential. This reagent is particularly useful for assessing neuronal activity and is applicable in studies involving the embryonic central nervous system. Its sensitivity to voltage fluctuations makes it an essential tool in neurobiology and electrophysiological research. -
Fluorescence Dye
6-Carboxy-X-rhodamine, succinimidyl ester is a fluorescent dye specifically designed for oligonucleotide labeling. This compound exhibits high stability and fluorescence intensity, making it suitable for applications in automated DNA sequencing and molecular biology research. It enables effective visualization of nucleic acids in various assays, improving the accuracy and efficiency of genetic analyses. -
Fluorescent DNA Stain
Br-DAPI is a fluorescent DNA stain that selectively binds to the minor groove of double-stranded DNA, particularly targeting AT-rich regions. This compound enhances fluorescence intensity approximately 20-fold upon binding, making it suitable for quantifying DNA concentration via fluorescence microscopy. Additionally, Br-DAPI can penetrate intact cell membranes, allowing for staining of both live and fixed cells, thus facilitating various applications in cell biology and molecular research. Store away from light to maintain stability. -
NIR Fluorescent Sensor
NIR-H2O2 is a cell-permeable near-infrared (NIR) fluorescent sensor designed to detect hydrogen peroxide (H2O2). Upon excitation in the NIR region, NIR-H2O2 exhibits a significant turn-on fluorescence response, enabling the sensitive imaging of endogenously produced H2O2 in living cells and mice. This compound is valuable for studying oxidative stress, signaling pathways, and various biological processes involving reactive oxygen species. -
Magnesium Fluorescent Probe
KMG-104AM is a membrane-permeable fluorescein-derived probe that specifically targets magnesium ions (Mg2+). This reagent facilitates intracellular imaging of magnesium in PC12 cells, enabling the visualization and study of magnesium dynamics within live cells. Its application in 3D imaging provides valuable insights into cellular magnesium homeostasis and its role in various physiological processes. -
Mitochondrial Membrane Potential Fluorescent Dye
TMRM (Tetramethylrhodamine Methyl Ester) is a membrane-permeable cationic fluorescent dye that selectively targets mitochondrial membrane potential. Its ability to accumulate in mitochondria results in strong fluorescence, enabling the visualization of mitochondrial dynamics. TMRM is widely utilized in cellular research, including studies of mitochondrial function, cell viability, and apoptosis in various biological systems, including animal, plant, and microbial cells. -
Fluorescent Compound
DMA trihydrochloride is a fluorescent compound with an excitation wavelength of 340 nm and an emission wavelength of 478 nm. This compound exhibits significant fluorescence properties, making it suitable for various biological imaging applications. It can be utilized in cellular studies, particularly in tracking and visualizing cellular processes in live cells. -
Fluorescent Probe
MitoPeDPP is a mitochondrial-targeted fluorescent probe that detects lipid peroxidation (LPO) within mitochondria. Synthesized from diphenylpyrenephosphine, this reagent enables the visualization of LPO events, making it valuable for studying mitochondrial dynamics in various biological contexts. Its application includes investigating RSL3-induced ferroptosis in oligodendrocytes, providing insights into the mechanisms of cell death and oxidative stress. -
Fluorescent Dye
QSY-21 is a powerful fluorescence quencher designed for applications in fluorescence resonance energy transfer (FRET). It exhibits broad absorption in the far red and near-infrared range, with a notable absorption maximum at 661 nm, enabling efficient quenching of fluorescence from dyes such as Cyanine5, Cyanine5.5, and AF 647. As a carboxylic acid derivative, QSY-21 is essential for studies requiring precise control of fluorescent signals, making it a valuable tool in various biochemical and cellular research applications. -
Fluorescent Probe
8-(4-Iodophenyl)-1,3,5,7-tetramethyl BODIPY is a BODIPY derivative designed for use as a fluorescent probe targeting GFP-labeled muscarinic M1 receptors. This compound exhibits strong fluorescence properties, enabling effective visualization and study of receptor interactions and dynamics in biological systems. Its application in research enhances the understanding of muscarinic receptor function and signaling pathways. -
Potassium Fluorescent Indicator
Asante potassium green-2 (TMA) is a cell-impermeable potassium-sensitive fluorescent indicator with an excitation/emission spectrum of 525/545 nm. It selectively detects intracellular potassium ion concentrations, making it valuable for studies involving ion channel activity and cellular signaling. This reagent is essential for investigating potassium homeostasis and its implications in various physiological processes and pathologies.
