Dyes

C12 Lissamine-rhodamine galactosylceramide (d18:1/12:0) is a fluorescently labeled derivative of C12 galactosylceramide. This compound targets glycosphingolipid metabolism and serves as a vital tool in the visualization of galactosylceramide in biological systems. Its unique fluorescent properties facilitate applications in live-cell imaging and studies of cell membrane dynamics, enhancing the understanding of glycosphingolipid function in cellular processes.

BODIPY-FL-Vindoline is a high-affinity fluorescent probe targeting the pregnane X receptor (PXR), exhibiting a dissociation constant (Kd) of 256 nM. This reagent serves as an essential tool for investigating drug metabolism and drug-drug interactions, enabling researchers to elucidate the regulatory mechanisms of PXR in pharmacological processes.

MB 660R NHS Ester is a far-red fluorescent dye that features a terminal NHS ester group, enabling targeted conjugation. With a maximum absorption at 665 nm and emission at 690 nm, this dye is suitable for a variety of labeling applications. It effectively labels primary amines (-NH2) in proteins, amine-modified oligonucleotides, and other amine-containing molecules, making it a valuable tool in biochemical research and fluorescence microscopy studies.

Cy5-bifunctional dye potassium is a water-soluble fluorescent dye featuring two terminal NHS ester functionalities. This reagent enables selective and efficient reactions with primary amines, such as those found in lysine residues or aminosilane-coated surfaces, under neutral to slightly basic conditions, resulting in stable covalent bonds. Its bifunctional nature makes it suitable for cross-conjugation of amines and a variety of advanced labeling applications in chemical and biological research.

TechnoDye 498/505 is a fluorescent dye that exhibits a broad absorption and emission spectrum similar to fluorescein. This compound demonstrates enhanced fluorescence in acidic environments and offers significant stability against photobleaching and oxidation. TechnoDye 498/505 is ideal for applications in cellular imaging, flow cytometry, and a variety of biochemical assays where robust fluorescence is essential.

5-Carboxyrhodamine 110 NHS ester is a fluorescent dye known for its bright and photostable green fluorescence, with excitation and emission maxima at approximately 502 nm and 527 nm, respectively. This amine-reactive dye is ideal for creating highly fluorescent bioconjugates and is preferred for applications requiring exceptional photostability and pH insensitivity within a range of 4 to 9. Its single isomer form facilitates improved resolution in HPLC purification, making it suitable for labeling proteins, peptides, and nucleotides in various biochemical research applications.

BP Fluor 405 NHS Ester is a water-soluble blue-fluorescent dye designed for use in multi-color applications such as flow cytometry and super-resolution microscopy, particularly STORM. Its excitation wavelength of 407 nm makes it well-suited for use with krypton lasers and violet laser diodes. The NHS ester group enables efficient labeling of primary amines in proteins, amine-modified oligonucleotides, and other amine-containing biomolecules, facilitating high-molar-conjugation without significant self-quenching. BP Fluor 405 conjugates are optimal for sensitive detection of target abundances in various research applications.

Cyanine3.5 dimethyl is a non-sulfonated cyanine dye known for its excellent solubility in organic solvents and bright fluorescence in the yellow-orange spectrum. This dye serves as a non-reactive fluorophore, making it suitable for control experiments, calibration, and various technical applications in fluorescence microscopy and imaging. Its properties enable precise studies in biological research, facilitating the visualization of cellular components and processes.

BP Fluor 430 NHS Ester is a water-soluble, green-fluorescent dye designed for use in multi-color applications, such as flow cytometry and super-resolution microscopy (STORM). It exhibits optimal excitation at 407 nm and 408 nm, making it compatible with krypton and violet laser sources. The NHS ester group enables efficient labeling of primary amines in proteins, amine-modified oligonucleotides, and other amine-containing molecules, maintaining pH insensitivity from pH 4 to pH 10. This dye allows for high molar ratio conjugation without significant self-quenching, resulting in brighter conjugates that enhance detection sensitivity.

DyLight 550 NHS ester is a fluorescent dye designed for advanced labeling applications in biochemical research. This vibrant orange-to-red fluorochrome exhibits superior performance compared to traditional rhodamine derivatives, facilitating enhanced detection and analysis. Its high water solubility allows for an optimal dye-to-protein ratio, ensuring efficient conjugation without precipitation of the labeled conjugates. DyLight 550 is ideal for applications such as immunofluorescence, flow cytometry, and live cell imaging.

Difluorocarboxyfluorescein cadaverine, 5-isomer, serves as a carbonyl-reactive fluorescent dye designed for the modification of carboxylic acids. This reagent can be utilized in conjunction with activators such as EDC or DCC, or with activated esters like NHS esters, to form stable amide bonds. It is valuable in various biochemical applications, including protein tagging, intracellular imaging, and studying molecular interactions via fluorescence.

BP Fluor 532 maleimide is a fluorescent dye that emits bright yellow fluorescence and remains photostable across a pH range of 4 to 10. Its excitation properties are optimal for the frequency-doubled Nd:YAG laser line, making it suitable for various applications in imaging and flow cytometry. The maleimide group allows for efficient conjugation with sulfhydryl-containing biomolecules such as proteins and peptides, creating stable thioether bonds and resulting in enhanced fluorescence intensity and photostability compared to other fluorophores.

BP Fluor 488 acid is a fluorescent dye targeting amine groups in biomolecules, including antibodies, proteins, peptides, and amino-modified oligonucleotides. This dye features an excitation peak at 499 nm and an emission peak at 520 nm, making it suitable for high-sensitivity applications. BP Fluor 488 acid conjugates are extensively utilized in microscopy and flow cytometry, enabling enhanced visualization and analysis of biological samples.

Cyanine3B azide is a fluorescent dye designed for click chemistry applications, specifically for conjugation with terminal alkynes via copper-catalyzed reactions or with strained cyclooctynes through copper-free methods. This yellow-emitting cyanine dye exhibits enhanced fluorescence quantum yield and photostability, attributed to its fixed conformation, making it one of the brightest dyes in its class. Due to its non-sulfonated nature, an organic co-solvent such as DMF or DMSO is recommended for optimal labeling efficiency in aqueous environments.

TAMRA DBCO, 5-isomer is a fluorescent dye derivative of tetramethylrhodamine (TMR) featuring a dibenzocyclooctyne (DBCO) moiety. It enables rapid and efficient labeling of azide-containing biomolecules through a sterically promoted azide-alkyne cycloaddition (SPAAC) reaction, eliminating the need for copper catalysts. This compound is suitable for a wide range of applications, including the labeling of proteins, peptides, and nucleic acids, facilitating advanced studies in biochemistry and cellular imaging.

5(6)-Carboxyrhodamine 110 NHS Ester is a fluorescent dye characterized by its amine-reactive functionality, enabling the formation of highly luminous and photostable green-fluorescent bioconjugates. With excitation and emission maxima at approximately 502 nm and 527 nm, respectively, this dye is particularly suited for applications in Fluorescence Correlation Spectroscopy (FCS). Its properties make it an excellent choice for studies requiring sensitive and reliable fluorescence detection in biological research.

OG 488 alkyne is a highly sensitive green-fluorescent dye designed for imaging azide-labeled biomolecules. It participates in copper-catalyzed azide-alkyne cycloaddition (CuAAC) to create a stable triazole linkage. This reagent is valuable for visualizing biomolecular interactions and dynamics, making it suitable for various applications in cellular imaging and bioconjugation studies.

BP Light 650 carboxylic acid is a vibrant far-red fluorochrome primarily utilized for fluorescent labeling applications. It demonstrates superior performance in comparison to traditional dyes, making it an effective choice for labeling antibodies and proteins as molecular probes. This reagent is suitable for cellular imaging and various fluorescence detection methods, facilitating advanced biological research.

BP Light 550 carboxylic acid is a fluorescent dye characterized by its vibrant orange-to-red emission spectra. This compound displays superior brightness and photostability compared to other rhodamine derivatives, making it ideal for advanced fluorescent applications. Its high water solubility facilitates efficient conjugation, enabling a high dye-to-protein ratio without precipitate formation, which is crucial for maintaining sample integrity in various research settings.

Cy5.5 dimethyl is a fluorescent dye that serves as a non-reactive fluorophore, making it ideal for use in experimental controls and instrument calibration. This non-sulfonated reagent exhibits excellent solubility in organic solvents and limited solubility in aqueous environments, facilitating a variety of research applications in optical imaging and fluorescence-based assays.

Sulfo-Cy5 picolyl azide is a fluorescent dye that incorporates an azide group, facilitating its use in click chemistry applications through reactivity with terminal alkynes and strained cyclooctynes. The Cy5 moiety provides effective fluorescence with excitation and emission maxima at 651 nm and 670 nm, respectively. The presence of the sulfonate group enhances the water solubility of this compound, making it suitable for various biological imaging and labeling studies. Its versatility allows for applications in biomolecular research, including protein tagging and cellular imaging.

Sulfo-Bis-(N,N'-carboxylic acid)-Cy5 is a fluorescent dye that displays the same absorbance and emission spectra as the Cy5 fluorophore. Its free unactivated carboxylic acid functional groups facilitate conjugation with biomolecules, making it suitable for various labeling applications in biological research. This compound is particularly useful in fluorescence microscopy, flow cytometry, and other imaging techniques requiring high sensitivity and specificity.

BP Fluor 405 acid is a water-soluble fluorescent dye that emits blue fluorescence, primarily utilized in multi-color applications such as flow cytometry and super-resolution microscopy, including STORM. Its excitation is optimal for the 407 nm spectral line of krypton lasers or 408 nm violet laser diodes, ensuring versatile usage across various experimental setups. The carboxylic acid functionality facilitates the synthesis of custom activated esters, such as sulfo-NHS and TFP, which may not be readily available. Additionally, it plays a significant role in peptide modification during solid-phase synthesis, often requiring in-situ activation with coupling reagents. BP Fluor 405 acid is also employed for calibration and control experiments.

BP Fluor 594 NHS ester is a fluorescent dye that targets primary amines in proteins, antibodies, and amine-modified oligonucleotides for efficient labeling. It forms stable, covalent amide bonds at pH 7-9, allowing for high molar ratio conjugations without significant self-quenching. This results in brighter conjugates conducive to sensitive detection applications. BP Fluor 594 exhibits excellent water solubility and is pH-insensitive from 4 to 10, with absorption and emission maxima at 590 nm and 617 nm, respectively. It is suitable for use with 561 nm and 594 nm laser lines, making it ideal for imaging and flow cytometry.

BP Fluor 488 TCO is a fluorescent dye that participates in the inverse-electron demand Diels-Alder cycloaddition reaction, reacting rapidly and selectively with tetrazines to form stable covalent linkages. This biocompatible reaction occurs without the need for copper catalysts or elevated temperatures, exhibiting an exceptionally high reaction rate constant (k > 800 M-1 s-1). BP Fluor 488 TCO is ideal for applications in bioorthogonal labeling, visualization, and tracking of biomolecules in live cells and various biological studies.

ROX alkyne, 6-isomer is an alkyne derivative of the red-emitting fluorescent dye ROX (Rhodamine X, Rhodamine 101), known for its high quantum yield. This compound is particularly useful for fluorescent labeling of azide-containing biomolecules through copper-catalyzed click chemistry. Its applications include quantitative PCR and microscopy, making it an essential reagent for advanced imaging and detection in biochemical research.

MB 488 NHS ester is a fluorescent dye characterized by its terminal NHS ester group, primarily functioning as a fluorophore. Exhibiting a maximal absorption at 501 nm and emission at 524 nm, this green fluorescent, hydrophilic dye is designed for the effective labeling of primary amines (-NH2) in proteins, amine-modified oligonucleotides, and other amine-containing compounds. Its high reactivity and fluorescence properties make it suitable for a variety of biological imaging applications and studies in chemical biology.

ROX azide, 6-isomer is a reactive derivative of the Rhodamine X dye, specifically designed for use with alkyne-reactive applications. This pure 6-isomer fluorophore exhibits high brightness and fluorescence quantum yield, making it an excellent choice for biological imaging. It facilitates the labeling of alkyne and cycloalkyne-containing biomolecules through copper-catalyzed and copper-free click chemistry reactions, enabling precise tracking and visualization in various research applications.

BP Light 800 NHS ester is a hydrophilic fluorescent dye that reacts with amines, allowing for effective conjugation to antibodies. This compound exhibits strong fluorescent properties, making it suitable for various applications such as western blotting, microscopy, flow cytometry, and cell-based assays. Its high dye-to-protein ratio enhances detection sensitivity and specificity in biological research.

FAM phosphoramidite, 5-isomer is a fluorescent dye specifically designed for 5'-terminal labeling of oligonucleotides. This high-purity single isomer exhibits excellent fluorescent properties, making it suitable for various applications in molecular biology, including DNA sequencing, hybridization assays, and real-time PCR. It enables enhanced visualization and tracking of nucleic acids in various experimental settings.

Sulfo-Cyanine5.5 carboxylic acid potassium is a fluorescent dye characterized by its excitation and emission wavelengths of 673 nm and 707 nm, respectively. The incorporation of a sulfite group significantly improves the compound's hydrophilicity, facilitating its application in aqueous environments. The terminal carboxylic acid group can readily react with primary amines, especially in the presence of coupling agents like EDC and HATU, enabling the formation of stable amide bonds for various biochemical applications, including labeling and tracking biomolecules in research studies.

FAM amine, 5-isomer is a fluorescein-based fluorescent dye that features an amine group enhancing reactivity with carboxylic acids and activated NHS esters. This compound is primarily utilized in bioconjugation applications and fluorescent labeling techniques. Its ability to undergo enzymatic transamination facilitates the attachment to various biomolecules for effective visualization and tracking in biological research.

FAM hydrazide, 5-isomer is a fluorescent dye linker featuring a hydrazide functional group that facilitates conjugation with aldehydes to form stable hydrazone bonds. This compound exhibits bright fluorescence, making it suitable for various applications in biochemical assays and bioconjugation techniques. Its universal properties as a fluorescein dye allow for its use in a wide range of research settings, including cellular imaging and detection assays.

QSY-9-succinimidyl ester is a nonfluorescent acceptor molecule that features a terminal NHS ester group. It exhibits a broad and intense quenching capability in the 500-600 nm range, making it ideal for use in fluorescence resonance energy transfer (FRET) applications alongside fluorescent dyes emitting in this spectrum. The reactive NHS ester effectively labels primary amines (-NH2) on proteins, amine-modified oligonucleotides, and other amine-bearing compounds, facilitating diverse biochemical analyses and detection methodologies.

Cy7 alkyne chloride is a fluorescent dye derivative of Cyanine 7 (Cy7) featuring an alkyne functional group, with an excitation/emission wavelength of 740/770 nm. This reagent can undergo click chemistry reactions with azide-containing molecules, enabling the formation of stable covalent bonds. It is widely utilized in fluorescence imaging, bioconjugation applications, and cellular labeling studies, making it a valuable tool for researchers in bioorthogonal chemistry and related fields.

BODIPY 480/508-cholesteryl linoleate is a cell-permeable fluorescent dye that targets cholesterol-related processes. This compound is utilized to visualize and monitor cholesterol trafficking in isolated human monocyte-derived macrophages, providing valuable insights into cellular lipid dynamics. The fluorescence properties (Excitation/Emission = 480/508 nm) make it an effective tool for studying cholesterol metabolism and related biological activities in various research applications.

Fluorescein O-acrylate is a fluorescent dye characterized by its efficient quantum yield in aqueous solutions, with excitation and emission wavelengths in the visible light spectrum. This versatile monomer can be copolymerized with various compounds, such as styrene and acrylamide, facilitating the formation of stable polymers that can bond with macromolecules. Key applications include its use in bioimaging and fluorescence-based assays, making it valuable for research in biochemistry and molecular biology.

NBDA (4-(α-N-L-alanine)-NBD) is a fluorescent analog of the 2,4-dinitrophenyl group (DNP) that serves as a valuable tool for detection and characterization of antinitroaromatic antibodies. Its unique properties enable the identification of antibodies even within crude biological samples and may facilitate investigations of cellular interactions on cell surfaces. This reagent is particularly useful in immunology and biochemical research applications.

SKM 4-45-1 is a fluorescent analog of Anandamide (AEA) designed for the study of transmembrane carrier-mediated transport mechanisms. This reagent enables researchers to investigate the cellular uptake and trafficking of AEA across cell membranes, facilitating a deeper understanding of endocannabinoid signaling pathways and their biological implications. SKM 4-45-1 is suitable for various applications in biochemical and pharmacological research.

Acid Blue 120 is an azo dye known for its fluorescent properties. It exhibits various biological activities, making it suitable for applications in textile dyeing, food and pharmaceutical coloring, as well as serving as a photosensitizer and sensor. Additionally, it can be used for surface modification in research studies.

4-(5)-(((4-ChloroMethyl)Benzoyl)AMino)TetraMethylrhodaMine is a multifunctional dye that serves as a vital tool in biological research. It facilitates the observation and analysis of cell structures, tracking of biomolecules, assessment of cell functions, and differentiation of cell types. Additionally, this dye is valuable for detecting biomolecules, studying tissue pathology, and monitoring microorganisms. Its versatile applications extend from fundamental scientific studies to clinical diagnostics, as well as in industrial areas such as textile dyeing and emerging technologies like dye-sensitized solar cells.

Pigment Red 21 is a multifunctional dye primarily utilized for biological research applications. This compound enhances visualization in various biological experiments, aiding in the observation and analysis of cell structures, tracking of biomolecules, and evaluation of cell functions. Its diverse applications extend from fundamental scientific research to clinical diagnostics, as well as traditional textile dyeing and emerging fields such as food pigments and dye-sensitized solar cells. Pigment Red 21 serves as a valuable tool for distinguishing cell types, detecting biomolecules, studying tissue pathology, and monitoring microorganisms.

Fluorescent Brightener 210 is a multifunctional dye that serves as a vital tool in biological research. It facilitates the observation and analysis of cell structures, tracking of biomolecules, evaluation of cell functions, and identification of distinct cell types. Additionally, it is applicable in studying tissue pathology and monitoring microorganisms. Beyond biological applications, it is also utilized in traditional textile dyeing and emerging fields such as functional textile processing, food pigments, and dye-sensitized solar cells.

Reactive Red 24 is a multifunctional dye primarily utilized for biological staining applications. This compound exhibits strong selectivity for proteins and nucleic acids, facilitating the observation and analysis of cell structures, tracking of biomolecules, and evaluation of cellular functions. Its diverse applications extend from basic research to clinical diagnostics, as well as traditional uses in textile dyeing and emerging areas including functional textiles, food pigments, and dye-sensitized solar cells.

C.I. Pigment Red 187 is a versatile dye that serves as a crucial tool in biological research. It enables scientists to visualize and analyze cell structures, track biomolecules, and assess cellular functions, making it invaluable for distinguishing cell types and detecting biomolecules. This dye is applicable in various fields, from fundamental scientific studies to clinical diagnostics, as well as in traditional applications such as textile dyeing and innovative uses in food pigmentation and dye-sensitized solar cells.

Disperse Green 9 is a multifunctional dye primarily utilized for staining and labeling in biological research. This compound enables the visualization of cell structures, tracking of biomolecules, evaluation of cellular functions, and differentiation of cell types. It serves diverse applications in scientific studies and diagnostic processes, alongside traditional uses in textile dyeing and innovative areas such as functional textiles and dye-sensitized solar cells.

Acid Red 266 is a multifunctional dye that serves as a vital tool in biological research. It facilitates the observation and analysis of cell structures, tracking of biomolecules, evaluation of cell functions, and differentiation of cell types. Its applications extend from fundamental scientific inquiries to various diagnostic uses, while also being relevant in textile dyeing, functional textile processing, food coloring, and dye-sensitized solar cells.

Procion Red MX 8B is a multifunctional azo dye primarily used for biological staining. This dye is instrumental in visualizing and analyzing cellular structures, tracking biomolecules, and assessing cell functionalities. Its applications span basic research, tissue pathology studies, and microbiological monitoring, making it valuable in both scientific investigations and clinical diagnostics. Additionally, Procion Red MX 8B serves roles in areas such as textile dyeing, food pigmentation, and the development of dye-sensitized solar cells.

Disperse Blue 291 is a multifunctional dye with versatile applications in biological research. It facilitates the observation and analysis of cellular structures, tracking of biomolecules, assessment of cell functions, and differentiation of cell types. Additionally, this dye is valuable for biomolecule detection, tissue pathology studies, and monitoring microorganisms. Beyond its use in scientific research, Disperse Blue 291 is also utilized in traditional textile dyeing and emerging applications, including functional textiles, food pigments, and dye-sensitized solar cells.

Basic Yellow 28 is a cationic dye primarily utilized for its fluorescent properties in biological applications. This multifunctional dye enables researchers to observe and analyze cellular structures, track biomolecules, and distinguish between various cell types. Its versatility extends to evaluating cell functions, detecting biomolecules, studying tissue pathology, and monitoring microorganisms, making it invaluable in both basic research and clinical diagnostics. Additionally, Basic Yellow 28 finds applications in traditional textile dyeing and emerging sectors such as food pigments and dye-sensitized solar cells.