Dynasore

Catalog No.: A12726

Dynamin inhibitor

Dynasore

Dynasore Chemical Structure

CAS NO. 304448-55-3

Dynasore is a non-competitive inhibitor of dynamin 1, dynamin 2 and mitochondrial dynamin (Drp1) GTPase activity

Availability: In stock

Package Price Qty
10 mg
$40.00
25 mg
$80.00
50 mg
$140.00
100 mg
$250.00
10mM * 1mL in DMSO
$72.00
Custom Size Get quote

Free Overnight Delivery on orders over $500

Next day delivery by 10:00 a.m. Order now.

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Tsukamoto H, .et al. Lipopolysaccharide (LPS)-binding protein stimulates CD14-dependent Toll-like receptor 4 internalization and LPS-induced TBK1-IKKε-IRF3 axis activation, J Biol Chem, 2018, Jun 29;293(26):10186-10201 PMID: 29760187
  • Shigetoshi Yokoyama, .et al. A novel pathway of LPS uptake through syndecan-1 leading to pyroptotic cell death, eLife, 2018, 7: e37854 PMID: 30526845
  • Naoko Fujii, .et al. Hypotonic Stress-induced Down-regulation of Claudin-1 and -2 Mediated by Dephosphorylation and Clathrin-dependent Endocytosis in Renal Tubular Epithelial Cells, J Biol Chem, 2016, Nov 18; 291(47): 24787-24799 PMID: 27733684

Biological Activity

Dynasore is a non-competitive inhibitor of dynamin 1, dynamin 2 and mitochondrial dynamin (Drp1) GTPase activity
Targets
Dynamin1/2 (Cell-free assay)
~15 μM
In vitro DMSO 64 mg/mL (198.56 mM)
Water <1 mg/mL (<1 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 31.03 mL 155.13 mL 310.25 mL
0.5 mM 6.21 mL 31.03 mL 62.05 mL
1 mM 3.1 mL 15.51 mL 31.03 mL
5 mM 0.62 mL 3.1 mL 6.21 mL

*The above data is based on the productmolecular weight 322.32. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12726
Actions Inhibitor
M. Wt 322.32
Formula C18H14N2O4
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 304448-55-3
SMILES C1=CC=C2C=C(C(=CC2=C1)C(=O)NN/C=C/3\C=CC(=O)C(=C3)O)O

Product Tags

Product Tags

Other people marked this product with these tags:

Use spaces to separate tags. Use single quotes (') for phrases.

Product Questions

Product Questions

No Questions
Keywords:buy Dynasore | Dynasore Supplier | purchase | cost | manufacturer | order | distributor | buy 304448-55-3| 304448-55-3 Supplier | purchase 304448-55-3 | 304448-55-3 cost | 304448-55-3 manufacturer | order 304448-55-3 | 304448-55-3 distributor
Rewards