Dynorphin A (1-10) is an endogenous opioid neuropeptide that acts as an agonist at the κ-opioid receptor, specifically binding to extracellular loop 2. Its biological activity includes the modulation of pain pathways and effects on mood regulation. Additionally, Dynorphin A (1-10) inhibits NMDA receptor-activated currents with an IC50 of 42.0 μM, making it a valuable tool for research into pain, addiction, and neuroprotection. This peptide is essential for studying opioid receptor dynamics and their implications in neurological disorders.
Dynorphin A (1-10) is an endogenous opioid neuropeptide that acts as an agonist at the κ-opioid receptor, specifically binding to extracellular loop 2. Its biological activity includes the modulation of pain pathways and effects on mood regulation. Additionally, Dynorphin A (1-10) inhibits NMDA receptor-activated currents with an IC50 of 42.0 μM, making it a valuable tool for research into pain, addiction, and neuroprotection. This peptide is essential for studying opioid receptor dynamics and their implications in neurological disorders.
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