E-4031 dihydrochloride

Catalog No.: A12857

K+ channel blocker‎

E-4031 dihydrochloride

E-4031 dihydrochloride Chemical Structure

CAS NO. 113559-13-0

E-4031 dihydrochloride is a selective blocker of KV11.1 (hERG) channels; inhibits the rapid delayed-rectifier K+ current (IKr).

Availability: In stock

Package Price Qty
10 mg
$105.00
25 mg
$240.00
50 mg
$450.00
100 mg
$850.00
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Biological Activity

E-4031 dihydrochloride is a selective blocker of KV11.1 (hERG) channels; inhibits the rapid delayed-rectifier K+ current (IKr).
In vitro DMSO 28 mg/mL (59.01 mM)
Water 44 mg/mL (92.74 mM)
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.08 mL 105.39 mL 210.77 mL
0.5 mM 4.22 mL 21.08 mL 42.15 mL
1 mM 2.11 mL 10.54 mL 21.08 mL
5 mM 0.42 mL 2.11 mL 4.22 mL

*The above data is based on the productmolecular weight 474.44. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12857
Actions Blocker
CAS No. 113559-13-0
Formula C21H27N3O3S.2HCl
M. Wt 474.44
Purity >98%
Synonyms E4031, E 4031
SMILES CC1=NC(=CC=C1)CCN2CCC(CC2)C(=O)C3=CC=C(C=C3)NS(=O)(=O)C.Cl.Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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