(E)-JP-2-196 TFA is a molecular glue handle that specifically interacts with E3-ubiquitin ligases, including RNF126, LRSAM1, RNF40, MID2, and RNF14, in vitro. This compound facilitates the synthesis of molecular glue degraders, making it a valuable tool for studying targeted protein degradation and investigating ubiquitin-proteasome system pathways. Its unique binding capabilities lend themselves to various research applications in protein modulation and therapeutic development.
(E)-JP-2-196 TFA is a molecular glue handle that specifically interacts with E3-ubiquitin ligases, including RNF126, LRSAM1, RNF40, MID2, and RNF14, in vitro. This compound facilitates the synthesis of molecular glue degraders, making it a valuable tool for studying targeted protein degradation and investigating ubiquitin-proteasome system pathways. Its unique binding capabilities lend themselves to various research applications in protein modulation and therapeutic development.
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