(E/Z)-OT-R antagonist 1 is a mixture of E and Z isomers that functions as a selective, non-peptide antagonist of the oxytocin receptor (OT-R). This compound effectively inhibits oxytocin-induced intracellular calcium activation, exhibiting an IC50 value of 8 nM. Its potent antagonistic activity makes it a valuable tool for investigating the role of oxytocin signaling in various biological processes and pathological conditions. Researchers can utilize this reagent in studies related to neurobiology, reproductive health, and stress response mechanisms.
(E/Z)-OT-R antagonist 1 is a mixture of E and Z isomers that functions as a selective, non-peptide antagonist of the oxytocin receptor (OT-R). This compound effectively inhibits oxytocin-induced intracellular calcium activation, exhibiting an IC50 value of 8 nM. Its potent antagonistic activity makes it a valuable tool for investigating the role of oxytocin signaling in various biological processes and pathological conditions. Researchers can utilize this reagent in studies related to neurobiology, reproductive health, and stress response mechanisms.
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