E0714 is a selective activator of the Kv7.2 potassium channel, exhibiting EC50 values of 1.90 μM for homotetrameric Kv7.2 channels and 0.021 μM for heterotetrameric Kv7.2/7.3 channels. This compound effectively crosses the blood-brain barrier and demonstrates anticonvulsant properties. E0714 is suitable for research applications focused on epilepsy and related neurological disorders.
E0714 is a selective activator of the Kv7.2 potassium channel, exhibiting EC50 values of 1.90 μM for homotetrameric Kv7.2 channels and 0.021 μM for heterotetrameric Kv7.2/7.3 channels. This compound effectively crosses the blood-brain barrier and demonstrates anticonvulsant properties. E0714 is suitable for research applications focused on epilepsy and related neurological disorders.
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