E3 Ligase Ligand-linker Conjugate 108

Catalog No.: A80439
E3 Ligase Ligand-linker Conjugate
E3 Ligase Ligand-linker Conjugate 108 is an E3 ligase ligand-linker conjugate designed for the synthesis of targeted protein degradation compounds. This reagent facilitates the development of PROTACs, specifically enabling the degradation of the SOS1 protein. It serves as a crucial tool in research applications focused on targeted protein modulation and therapeutic intervention in cellular processes related to disease states.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionE3 Ligase Ligand-linker Conjugate 108 is an E3 ligase ligand-linker conjugate designed for the synthesis of targeted protein degradation compounds. This reagent facilitates the development of PROTACs, specifically enabling the degradation of the SOS1 protein. It serves as a crucial tool in research applications focused on targeted protein modulation and therapeutic intervention in cellular processes related to disease states.
Product Information
Catalog NumA80439
FormulaC22H26ClN3O4
Molecular Weight431.91
CAS Number2911613-56-2
SMILESO=C(C1=CC(N2CCC(NC2=O)=O)=C(Cl)C=C1)N3CCC4(CC3)CCC(CC4)C=O
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This equation is commonly abbreviated as: C1V1 = C2V2

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