E3 Ligase Ligand-Linker Conjugate 116 is designed as a ligand-linker conjugate targeting E3 ubiquitin ligases. This compound facilitates the synthesis of PROTAC SMARCA2/4-degrader-28, enabling selective protein degradation through the ubiquitin-proteasome system. Its applications are particularly significant in studying mechanisms of protein regulation and the development of targeted therapeutics in cancer research.
E3 Ligase Ligand-Linker Conjugate 116 is designed as a ligand-linker conjugate targeting E3 ubiquitin ligases. This compound facilitates the synthesis of PROTAC SMARCA2/4-degrader-28, enabling selective protein degradation through the ubiquitin-proteasome system. Its applications are particularly significant in studying mechanisms of protein regulation and the development of targeted therapeutics in cancer research.
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