E3 Ligase Ligand-linker Conjugate 170 is a specialized conjugate that facilitates the synthesis of PROTACs by incorporating an E3 ligase ligand with a linker. This compound demonstrates potent anti-proliferative activity in non-Hodgkin's lymphoma cell line SU-DHL-4, exhibiting an IC50 value of less than 0.2 μM. It is an essential tool for researchers investigating targeted protein degradation pathways and their implications in cancer therapeutics.
E3 Ligase Ligand-linker Conjugate 170 is a specialized conjugate that facilitates the synthesis of PROTACs by incorporating an E3 ligase ligand with a linker. This compound demonstrates potent anti-proliferative activity in non-Hodgkin's lymphoma cell line SU-DHL-4, exhibiting an IC50 value of less than 0.2 μM. It is an essential tool for researchers investigating targeted protein degradation pathways and their implications in cancer therapeutics.
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