E3 Ligase Ligand-Linker Conjugate 50 is a conjugate comprising an E3 ligase ligand, (S,R,S)-AHPC, and a corresponding linker. The (S,R,S)-AHPC is derived from the VH032 structure and functions as a selective ligand for von Hippel-Lindau (VHL) proteins, facilitating targeted protein degradation. This conjugate serves as a crucial intermediate in the synthesis of complete PROTAC molecules, enabling applications in drug discovery and development aimed at modulating protein levels in various biological systems.
E3 Ligase Ligand-Linker Conjugate 50 is a conjugate comprising an E3 ligase ligand, (S,R,S)-AHPC, and a corresponding linker. The (S,R,S)-AHPC is derived from the VH032 structure and functions as a selective ligand for von Hippel-Lindau (VHL) proteins, facilitating targeted protein degradation. This conjugate serves as a crucial intermediate in the synthesis of complete PROTAC molecules, enabling applications in drug discovery and development aimed at modulating protein levels in various biological systems.
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