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Biological Activity
E7820 is a small molecule and aromatic sulfonamide derivative with potential antiangiogenic and antitumor activities. E7820 inhibits angiogenesis by suppressing integrin alpha 2, a cell adhesion molecule expressed on endothelial cells.
| In vitro | DMSO | 64 mg/mL (190.26 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 29.73 mL | 148.65 mL | 297.29 mL |
| 0.5 mM | 5.95 mL | 29.73 mL | 59.46 mL |
| 1 mM | 2.97 mL | 14.86 mL | 29.73 mL |
| 5 mM | 0.59 mL | 2.97 mL | 5.95 mL |
*The above data is based on the productmolecular weight 336.37. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15456 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 289483-69-8 |
| Formula | C17H12N4O2S |
| M. Wt | 336.37 |
| Purity | >98% |
| Synonyms | E 7820, E-7820 |
| SMILES | CC1=C2C(=CNC2=C(C=C1)NS(=O)(=O)C3=CC=CC(=C3)C#N)C#N |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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