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EC 313

Catalog No.: A85267
Progesterone Receptor Modulator
EC 313 is a selective progesterone receptor modulator that effectively targets the progesterone receptor. It demonstrates dose-dependent efficacy in reducing the weight of uterine fibroids and can decrease the expression of estrogen receptor (ER) and progesterone receptor (PR). EC 313 is a valuable tool for investigating the biological mechanisms underlying uterine fibroids and their treatment.
EC 313 1249398-29-5 Progesterone Receptor Modulator
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEC 313 is a selective progesterone receptor modulator that effectively targets the progesterone receptor. It demonstrates dose-dependent efficacy in reducing the weight of uterine fibroids and can decrease the expression of estrogen receptor (ER) and progesterone receptor (PR). EC 313 is a valuable tool for investigating the biological mechanisms underlying uterine fibroids and their treatment.
Product Information
Catalog NumA85267
FormulaC32H32F2O3
Molecular Weight502.59
CAS Number1249398-29-5
SMILESC[C@@]12[C@@]3(CC[C@@]1([H])[C@@]4([H])C([C@@H](C5=CC=C(C6=COC=C6)C=C5)C2)=C7C(CC4)=CC(CC7)=O)/C(CCO3)=C(F)/F
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Endocrinology-Hormones > Progesterone Receptors