EGFR-IN-112 is a potent inhibitor of the EGFR kinase, exhibiting IC50 values of 2.31 ± 0.3 μM in MCF-7, 3.16 ± 0.8 μM in H69AR, and 4.2 ± 0.2 μM in PC-3 cancer cell lines. This compound shows selective cytotoxicity towards cancer cells, making it a valuable tool for research in targeted cancer therapies and investigations into EGFR-related signaling pathways. Its efficacy highlights its potential in the study of cancer resistance mechanisms and the development of novel anticancer treatments.
EGFR-IN-112 is a potent inhibitor of the EGFR kinase, exhibiting IC50 values of 2.31 ± 0.3 μM in MCF-7, 3.16 ± 0.8 μM in H69AR, and 4.2 ± 0.2 μM in PC-3 cancer cell lines. This compound shows selective cytotoxicity towards cancer cells, making it a valuable tool for research in targeted cancer therapies and investigations into EGFR-related signaling pathways. Its efficacy highlights its potential in the study of cancer resistance mechanisms and the development of novel anticancer treatments.
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