EGFR-IN-15

Catalog No.: A28831
EGFR Inhibitor
EGFR-IN-15 is a potent inhibitor of the epidermal growth factor receptor (EGFR), exhibiting an IC50 of 4 nM. This compound is pivotal for research in oncological diseases, allowing for the exploration of EGFR signaling pathways and their role in tumorigenesis. Its high specificity and efficacy make it a valuable tool for therapeutic investigations and drug development targeting EGFR-driven malignancies.
Grouped product items
Size Price Stock Qty
5mg
$95.00
In stock
10mg
$155.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEGFR-IN-15 is a potent inhibitor of the epidermal growth factor receptor (EGFR), exhibiting an IC50 of 4 nM. This compound is pivotal for research in oncological diseases, allowing for the exploration of EGFR signaling pathways and their role in tumorigenesis. Its high specificity and efficacy make it a valuable tool for therapeutic investigations and drug development targeting EGFR-driven malignancies.
Product Information
Catalog NumA28831
FormulaC24H25BrN6O2
Molecular Weight509.40
CAS Number2573869-16-4
SMILESC[C@H]1CN2C3=CC(Br)=CC=C3N/C2=N\C(C4=CC(C)=NC(C5=C(N(N=C5)C)OCCC1)=C4)=O
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