EGFR-IN-180 is a potent inhibitor of the epidermal growth factor receptor (EGFR), specifically targeting both wild-type and the drug-resistant L858R/T790M/C797S mutation, with IC50 values of 80.96 nM and 16.43 nM, respectively. This compound serves as an important tool for investigating therapeutic options in non-small cell lung cancer (NSCLC) research, enabling studies on resistance mechanisms and potential combination therapies. Its specific action on EGFR pathways makes it a valuable reagent in cancer biology and pharmacological development.
EGFR-IN-180 is a potent inhibitor of the epidermal growth factor receptor (EGFR), specifically targeting both wild-type and the drug-resistant L858R/T790M/C797S mutation, with IC50 values of 80.96 nM and 16.43 nM, respectively. This compound serves as an important tool for investigating therapeutic options in non-small cell lung cancer (NSCLC) research, enabling studies on resistance mechanisms and potential combination therapies. Its specific action on EGFR pathways makes it a valuable reagent in cancer biology and pharmacological development.
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