EGFR-IN-23 is a potent inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase, exhibiting an IC50 of 8.05 nM in BaF3 cells expressing the EGFR-DEL19/T790M/C797S mutation. This compound demonstrates significant effectiveness in inhibiting cell proliferation associated with oncogenic EGFR signaling. EGFR-IN-23 is suitable for research applications focused on cancer biology, particularly in studies investigating resistance mechanisms in targeted therapies.
EGFR-IN-23 is a potent inhibitor of the epidermal growth factor receptor (EGFR) tyrosine kinase, exhibiting an IC50 of 8.05 nM in BaF3 cells expressing the EGFR-DEL19/T790M/C797S mutation. This compound demonstrates significant effectiveness in inhibiting cell proliferation associated with oncogenic EGFR signaling. EGFR-IN-23 is suitable for research applications focused on cancer biology, particularly in studies investigating resistance mechanisms in targeted therapies.
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