EGFR-IN-36 is a selective inhibitor of the epidermal growth factor receptor (EGFR), exhibiting IC50 values of 19.09 nM, 120.01 nM, and 2.35 nM for wild-type EGFR, wild-type HER2, and the HER2 mutant A775_G776insYVMA, respectively. This compound demonstrates significant potential in research focused on tumor types driven by both wild-type and mutant forms of EGFR and HER2 kinases, making it a valuable tool for investigating targeted cancer therapies.
EGFR-IN-36 is a selective inhibitor of the epidermal growth factor receptor (EGFR), exhibiting IC50 values of 19.09 nM, 120.01 nM, and 2.35 nM for wild-type EGFR, wild-type HER2, and the HER2 mutant A775_G776insYVMA, respectively. This compound demonstrates significant potential in research focused on tumor types driven by both wild-type and mutant forms of EGFR and HER2 kinases, making it a valuable tool for investigating targeted cancer therapies.
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