EGFR-IN-69 is a highly selective inhibitor of the epidermal growth factor receptor (EGFR), demonstrating potent activity with IC50 values of 4.3 nM for EGFRL858R/T790M/C797S, 6.6 nM for EGFRL858R/T790M, and 25.6 nM for EGFR19del/T790M/C797S. This compound is particularly relevant for research in non-small-cell lung cancer (NSCLC), providing valuable insights into therapeutic strategies targeting mutant EGFR variants. Its efficacy in inhibiting EGFR activity makes it an important tool for advancing cancer research and drug development.
EGFR-IN-69 is a highly selective inhibitor of the epidermal growth factor receptor (EGFR), demonstrating potent activity with IC50 values of 4.3 nM for EGFRL858R/T790M/C797S, 6.6 nM for EGFRL858R/T790M, and 25.6 nM for EGFR19del/T790M/C797S. This compound is particularly relevant for research in non-small-cell lung cancer (NSCLC), providing valuable insights into therapeutic strategies targeting mutant EGFR variants. Its efficacy in inhibiting EGFR activity makes it an important tool for advancing cancer research and drug development.
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