EGFR Inhibitor

Catalog No.: A13673

EGFR Inhibitor

EGFR Inhibitor Chemical Structure

CAS NO. 879127-07-8

EGFR inhibitor is a cell permeable, 4,6-disubstituted pyrimidine compound that selectively inhibits the EGFR kinase with an IC50 value of 21 nM in vitro and blocks receptor autophosphorylation in cells.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $180.00

Special Price $144.00

10 mg

Regular Price: $300.00

Special Price $240.00

25 mg

Regular Price: $600.00

Special Price $480.00

Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

EGFR inhibitor is a cell permeable, 4,6-disubstituted pyrimidine compound that selectively inhibits the EGFR kinase with an IC50 value of 21 nM in vitro and blocks receptor autophosphorylation in cells.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.19 mL 120.95 mL 241.9 mL
0.5 mM 4.84 mL 24.19 mL 48.38 mL
1 mM 2.42 mL 12.09 mL 24.19 mL
5 mM 0.48 mL 2.42 mL 4.84 mL

*The above data is based on the productmolecular weight 413.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13673
Actions Inhibitor
M. Wt 413.4
Formula C21H18F3N5O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 879127-07-8
Synonyms Epidermal Growth Factor Receptor Inhibitor
SMILES C1CC1C(=O)NC2=CC=CC(=C2)NC3=NC=NC(=C3)NC4=CC=CC(=C4)C(F)(F)F

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