EGFR T790M/L858R-IN-7 is a potent inhibitor of the EGFR L858R and T790M mutations, demonstrating a remarkable 93% inhibition rate at a concentration of 0.05 μM. This novel pyrimidine compound operates by selectively targeting the kinase domain of the epidermal growth factor receptor (EGFR), effectively suppressing its phosphorylation activity. It is a valuable tool for research applications focused on understanding resistance mechanisms in non-small cell lung cancer (NSCLC) and developing targeted therapies.
EGFR T790M/L858R-IN-7 is a potent inhibitor of the EGFR L858R and T790M mutations, demonstrating a remarkable 93% inhibition rate at a concentration of 0.05 μM. This novel pyrimidine compound operates by selectively targeting the kinase domain of the epidermal growth factor receptor (EGFR), effectively suppressing its phosphorylation activity. It is a valuable tool for research applications focused on understanding resistance mechanisms in non-small cell lung cancer (NSCLC) and developing targeted therapies.
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