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EI1

EZH2 inhibitor

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Catalog No. A12711

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
EI1 5mg A12711-5
$95.00
EI1 10mg A12711-10
$160.00
EI1 50mg A12711-50
$480.00

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

EI1 is a potent and selective small molecule inhibitor of EZH2 with IC50 values of 15 nM and 13 nM for wild type EZH2 and EZH2 Y641F mutant, respectively.

EI1

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Chemical Information

Catalog Num A12711
Actions Inhibitor
M. Wt 390.48
Formula C23H26N4O2
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1418308-27-6
Synonyms Ezh2 inhibitor, EI-1, EI 1
SMILES CCC(CC)N1C=CC2=C(C=C(C=C21)C#N)C(=O)NCC3=C(C=C(NC3=O)C)C

Biological Activity

Description
EI1 is a potent and selective small molecule inhibitor of EZH2 with IC50 values of 15 nM and 13 nM for wild type EZH2 and EZH2 Y641F mutant, respectively.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 25.61 mL 128.05 mL 256.1mL
0.5 mM 5.12 mL 25.61 mL 51.22 mL
1 mM 2.56 mL 12.8 mL 25.61 mL
5 mM 0.51 mL 2.56 mL 5.12 mL

*The above data is based on the productmolecular weight 390.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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