Total item
Cart Subtotal
$0.00 - Tomasz Kostrzewski, .et al. Modelling human liver fibrosis in the context of non-alcoholic steatohepatitis using a microphysiological system, Commun Biol, 2021, 4: 1080 PMID: 34526653
- Joost Boeckmans, .et al. Flow cytometric quantification of neutral lipids in a human skin stem cell-derived model of NASH, MethodsX, 2020, 7: 101068 PMID: 33024711
- Joost Boeckmans, .et al. Human hepatic in vitro models reveal distinct anti-NASH potencies of PPAR agonists, Cell Biol Toxicol, 2020, Jul 1 PMID: 32613381
- Joost Boeckmans, .et al. Transcriptomics data of a human in vitro model of non-alcoholic steatohepatitis exposed to elafibranor, Data in Brief, 2019, June 3 PMID: 31294056
- Boeckmans J, .et al. Elafibranor restricts lipogenic and inflammatory responses in a human skin stem cell-derived model of NASH, Pharmacol Res, 2019, Apr 24. pii: S1043-6618(18)31850-4 PMID: 31028903
Biological Activity
Elafibranor is an agonist of the peroxisome proliferator-activated Receptor-α and -δ, induces resolution of nonalcoholic steatohepatitis without fibrosis worsening.
| In vitro | DMSO | 74 mg/mL (192.46 mM) | |
| Water | Insoluble | ||
| Ethanol | 74 mg/mL (192.46 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.01 mL | 130.04 mL | 260.08 mL |
| 0.5 mM | 5.2 mL | 26.01 mL | 52.02 mL |
| 1 mM | 2.6 mL | 13 mL | 26.01 mL |
| 5 mM | 0.52 mL | 2.6 mL | 5.2 mL |
*The above data is based on the productmolecular weight 384.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A15454 |
|---|---|
| Actions | Agonist |
| CAS No. | 923978-27-2 |
| Formula | C22H24O4S |
| M. Wt | 384.49 |
| Purity | >98% |
| Synonyms | GFT505, GFT-505, GFT 505 |
| SMILES | CC1=CC(=CC(=C1OC(C)(C)C(=O)O)C)C=CC(=O)C2=CC=C(C=C2)SC |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
Product Tags
Product Questions
Product Questions
No Questions
Keywords:buy Elafibranor | Elafibranor Supplier | purchase | cost | manufacturer | order | distributor | buy 923978-27-2| 923978-27-2 Supplier | purchase 923978-27-2 | 923978-27-2 cost | 923978-27-2 manufacturer | order 923978-27-2 | 923978-27-2 distributor
Adooq Quality Guarantee
We promise all products perform as described.