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Biological Activity
Elagolix is a Gonadotropin-Releasing Hormone (GnRH) Antagonist. Elagolix inhibits gonadatropin releasing hormone (GnRH) receptors in the pituitary gland and ultimately reduces circulating sex hormone levels.
| In vitro | DMSO | 96 mg/mL (146.88 mM) | |
| Water | 96 mg/mL (146.88 mM) | ||
| Ethanol | 96 mg/mL (146.88 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 15.3 mL | 76.5 mL | 153.01 mL |
| 0.5 mM | 3.06 mL | 15.3 mL | 30.6 mL |
| 1 mM | 1.53 mL | 7.65 mL | 15.3 mL |
| 5 mM | 0.31 mL | 1.53 mL | 3.06 mL |
*The above data is based on the productmolecular weight 653.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A13893 |
|---|---|
| Actions | Antagonist |
| CAS No. | 832720-36-2 |
| Formula | C32H29F5N3NaO5 |
| M. Wt | 653.57 |
| Purity | >98% |
| Synonyms | NBI-56418 Na |
| SMILES | CC1=C(C(=O)N(C(=O)N1CC2=C(C=CC=C2F)C(F)(F)F)C[C@@H](C3=CC=CC=C3)NCCCC(=O)[O-])C4=C(C(=CC=C4)OC)F.[Na+] |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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