Elbasvir (MK-8742)

Catalog No.: A16855

NS5A inhibitor

Elbasvir (MK-8742)

Elbasvir (MK-8742) Chemical Structure

CAS NO. 1370468-36-2

Elbasvir is an NS5A inhibitor, preventing hepatitis C viral RNA replication and virion assembly. Median EC50 values range from 0.2 to 3600?pmol/L, based on genotype.

Availability: In stock

Package Price Qty
2 mg
$80.00
5 mg
$120.00
10 mg
$160.00
50 mg
$520.00
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Biological Activity

Elbasvir is an NS5A inhibitor, preventing hepatitis C viral RNA replication and virion assembly. Median EC50 values range from 0.2 to 3600?pmol/L, based on genotype.
In vitro DMSO 99 mg/mL (112.24 mM)
Water Insoluble
Ethanol 99 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 11.34 mL 56.69 mL 113.38 mL
0.5 mM 2.27 mL 11.34 mL 22.68 mL
1 mM 1.13 mL 5.67 mL 11.34 mL
5 mM 0.23 mL 1.13 mL 2.27 mL

*The above data is based on the productmolecular weight 882.02. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A16855
Actions Inhibitor
CAS No. 1370468-36-2
Formula C49H55N9O7
M. Wt 882.02
Purity >98%
Synonyms MK8742, MK 8742
SMILES O=C([[email protected]](C(C)C)NC(OC)=O)N(CCC1)C1C(N2)=NC=C2C(C=C3)=CC4=C3N([[email protected]](C5=CC=CC=C5)OC6=C7C=CC(C8=CN=C([[email protected]@H]9CCCN9C([[email protected]@H](NC(OC)=O)C(C)C)=O)N8)=C6)C7=C4
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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