Biological Activity
Elbasvir is an NS5A inhibitor, preventing hepatitis C viral RNA replication and virion assembly. Median EC50 values range from 0.2 to 3600?pmol/L, based on genotype.
In vitro | DMSO | 99 mg/mL (112.24 mM) | |
Water | Insoluble | ||
Ethanol | 99 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 11.34 mL | 56.69 mL | 113.38 mL |
0.5 mM | 2.27 mL | 11.34 mL | 22.68 mL |
1 mM | 1.13 mL | 5.67 mL | 11.34 mL |
5 mM | 0.23 mL | 1.13 mL | 2.27 mL |
*The above data is based on the productmolecular weight 882.02. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A16855 |
---|---|
Actions | Inhibitor |
CAS No. | 1370468-36-2 |
Formula | C49H55N9O7 |
M. Wt | 882.02 |
Purity | >98% |
Synonyms | MK8742, MK 8742 |
SMILES | O=C([[email protected]](C(C)C)NC(OC)=O)N(CCC1)C1C(N2)=NC=C2C(C=C3)=CC4=C3N([[email protected]](C5=CC=CC=C5)OC6=C7C=CC(C8=CN=C([[email protected]@H]9CCCN9C([[email protected]@H](NC(OC)=O)C(C)C)=O)N8)=C6)C7=C4 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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