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NMDA antagonist

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Catalog No. A12946

Availability:Stock in USAIn stock

Product Name Catalog No. Price Qty
Eliprodil 10mg A12946-10
Eliprodil 25mg A12946-25
Eliprodil 50mg A12946-50

Products are for laboratory research use only. Not for human use. We do not sell to patients.

Quick Overview

Eliprodil is a non-competitive NR2B-NMDA receptor antagonist(IC50=1 uM), less potent for NR2A- and NR2C-containing receptors(IC50> 100 uM).


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Chemical Information

Catalog Num A12946
Actions Antagonist
M. Wt 347.86
Formula C20H23ClFNO
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 119431-25-3
Synonyms SL-820715, SL820715, SL 820715
SMILES ClC1=CC=C(C=C1)[[email protected]](CN2CCC(CC(C=C3)=CC=C3F)CC2)O

Biological Activity

Eliprodil is a non-competitive NR2B-NMDA receptor antagonist(IC50=1 uM), less potent for NR2A- and NR2C-containing receptors(IC50> 100 uM).

Preparing Stock Solutions

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 28.75 mL 143.74 mL 287.47mL
0.5 mM 5.75 mL 28.75 mL 57.49 mL
1 mM 2.87 mL 14.37 mL 28.75 mL
5 mM 0.57 mL 2.87 mL 5.75 mL

*The above data is based on the productmolecular weight 347.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

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