Catalog No.: A13780

DNA topoisomerase II inhibitor


Ellipticine Chemical Structure

CAS NO. 519-23-3

Ellipticine is a DNA intercalating agent and a DNA topoisomerase II inhibitor.

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  • Calhelha RC, .et al. Mathematical models of cytotoxic effects in endpoint tumor cell line assays: critical assessment of the application of a single parametric value as a standard criterion to quantify the dose-response effects and new unexplored proposal formats, Analyst, 2017, Oct 23;142(21):4124-4141 PMID: 28991301

Biological Activity

Ellipticine is a DNA intercalating agent and a DNA topoisomerase II inhibitor.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 40.6 mL 203 mL 405.99 mL
0.5 mM 8.12 mL 40.6 mL 81.2 mL
1 mM 4.06 mL 20.3 mL 40.6 mL
5 mM 0.81 mL 4.06 mL 8.12 mL

*The above data is based on the productmolecular weight 246.31. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13780
Actions Inhibitor
CAS No. 519-23-3
Formula C17H14N2
M. Wt 246.31
Purity >98%
Synonyms BRN 0221300, CCG-36483, CCRIS 2003, DB-052047

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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