Elomotecan

Catalog No.: A57167
Topoisomerases I/II Inhibitor
Elomotecan is a potent inhibitor of topoisomerases I and II, classified as a camptothecin analog within the homocamptothecin family. This compound exhibits significant cytotoxic activity against various tumor cell lines, demonstrating enhanced efficacy compared to standard anticancer agents targeting the same mechanisms. Elomotecan's ability to interfere with DNA replication and repair makes it a valuable tool in cancer research and drug development.
Grouped product items
Size Price Stock Qty
25mg
$5,715.00
In stock
50mg
$7,345.00
In stock
100mg
$9,805.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionElomotecan is a potent inhibitor of topoisomerases I and II, classified as a camptothecin analog within the homocamptothecin family. This compound exhibits significant cytotoxic activity against various tumor cell lines, demonstrating enhanced efficacy compared to standard anticancer agents targeting the same mechanisms. Elomotecan's ability to interfere with DNA replication and repair makes it a valuable tool in cancer research and drug development.
Product Information
Catalog NumA57167
FormulaC29H32ClN3O4
Molecular Weight522.04
CAS Number220998-10-7
SMILESO=C(OC1)C[C@](O)(CC)C2=C1C(N3CC4=C(CN5CCC(C)CC5)C6=CC(C)=C(Cl)C=C6N=C4C3=C2)=O
SynonymsBN 80927 free base
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