Emvistegrast

Catalog No.: A57437
α4β7 Integrin Inhibitor
Emvistegrast is a quinolone derivative that functions as a selective inhibitor of the α4β7 integrin. This compound demonstrates significant potential in modulating immune responses and is particularly relevant for research into inflammatory bowel disease and other conditions associated with α4β7 integrin activity. Its oral bioavailability allows for convenient administration in various preclinical studies, facilitating investigations into its therapeutic efficacy.
Grouped product items
Size Price Stock Qty
1mg
$215.00
In stock
5mg
$535.00
In stock
10mg
$780.00
In stock
25mg
$1,150.00
In stock
50mg
$1,515.00
In stock
100mg
$1,990.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEmvistegrast is a quinolone derivative that functions as a selective inhibitor of the α4β7 integrin. This compound demonstrates significant potential in modulating immune responses and is particularly relevant for research into inflammatory bowel disease and other conditions associated with α4β7 integrin activity. Its oral bioavailability allows for convenient administration in various preclinical studies, facilitating investigations into its therapeutic efficacy.
Product Information
Catalog NumA57437
FormulaC35H32F4N6O6
Molecular Weight708.66
CAS Number2417352-91-9
SMILESCCOC([C@H](CC1=CC=C(N2C(N(C3=C(C2=O)C=CN=C3)C)=O)C4=C1C=CC=N4)NC(C5=C(C=C(C=C5F)N6[C@H](COCC6)C(F)(F)F)C)=O)=O
SynonymsGS-1427
Useful Calculator

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