Enadoline (CI-977) is a highly selective nonpeptide agonist of the kappa-opioid receptor (KOR) with a Ki value of 1.25 nM, enabling effective brain penetration. It exhibits significant antinociceptive activity, making it a valuable tool for researching pain mechanisms and potential therapeutic applications in pain management and opioid research.
Enadoline (CI-977) is a highly selective nonpeptide agonist of the kappa-opioid receptor (KOR) with a Ki value of 1.25 nM, enabling effective brain penetration. It exhibits significant antinociceptive activity, making it a valuable tool for researching pain mechanisms and potential therapeutic applications in pain management and opioid research.
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