Enarodustat hydrochloride

Catalog No.: A75574
HIF/HIF Prolyl-Hydroxylase Inhibitor
Enarodustat hydrochloride is a potent inhibitor of hypoxia-inducible factor (HIF) and HIF prolyl-hydroxylase, exhibiting an EC50 of 0.22 μM. This compound is primarily investigated for its potential in the treatment of renal anemia by stabilizing HIF, thereby promoting erythropoiesis and improving oxygenation in tissues. It serves as a valuable tool for research in hypoxia-related pathways and anemia therapies.
Grouped product items
Size Price Stock Qty
25mg
$1,905.00
In stock
50mg
$2,445.00
In stock
100mg
$3,200.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEnarodustat hydrochloride is a potent inhibitor of hypoxia-inducible factor (HIF) and HIF prolyl-hydroxylase, exhibiting an EC50 of 0.22 μM. This compound is primarily investigated for its potential in the treatment of renal anemia by stabilizing HIF, thereby promoting erythropoiesis and improving oxygenation in tissues. It serves as a valuable tool for research in hypoxia-related pathways and anemia therapies.
Product Information
Catalog NumA75574
FormulaC17H17ClN4O4
Molecular Weight376.79
CAS Number1262131-60-1
SMILESO=C(C(C1=NC=NN1C(CCC2=CC=CC=C2)=C3)=C3O)NCC(O)=O.Cl
SynonymsJTZ-951 hydrochloride; SAL0951 hydrochloride
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