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Endoxifen

Catalog No.: A12639

Estrogen receptor antagonist

Endoxifen

Endoxifen Chemical Structure

CAS NO. 112093-28-4

Endoxifen is a secondary metabolite of tamoxifen. It is a primary metabolite responsible for the effectiveness of tamoxifen in ER-positive breast cancer.

Availability: In stock

Package Price Qty
10 mg
$70.00
25 mg
$140.00
50 mg
$220.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • Marina Arino Martin, .et al. Photolytic fate of (E)- and (Z)-endoxifen in water and treated wastewater exposed to sunlight, Environ Res, 2021, Apr 3;197:111121 PMID: 33823193
  • Martin MA, .et al. Photodegradation of (E)- and (Z)-Endoxifen in water by ultraviolet light: Efficiency, kinetics, by-products, and toxicity assessment, Water Res, 2019, Dec 29;171:115451 PMID: 31901682

Biological Activity

Endoxifen is a secondary metabolite of tamoxifen. It is a primary metabolite responsible for the effectiveness of tamoxifen in ER-positive breast cancer.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 26.77 mL 133.87 mL 267.74 mL
0.5 mM 5.35 mL 26.77 mL 53.55 mL
1 mM 2.68 mL 13.39 mL 26.77 mL
5 mM 0.54 mL 2.68 mL 5.35 mL

*The above data is based on the productmolecular weight 373.49. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12639
Actions Antagonist
CAS No. 112093-28-4
Formula C25H27NO2
M. Wt 373.49
Purity >98%
SMILES CCC(=C(C1=CC=C(C=C1)O)C2=CC=C(C=C2)OCCNC)C3=CC=CC=C3
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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