Enniatin A1 is a cyclic hexadepsipeptide that functions as an apoptosis inducer. Isolated from Fusarium mycotoxins, this compound exhibits anticarcinogenic properties primarily through the induction of apoptosis and disruption of the ERK signaling pathway. In addition, Enniatin A1 demonstrates inhibitory activity against acyl-CoA:cholesterol acyltransferase (ACAT) with an IC50 of 49 μM in rat liver microsomes, making it a valuable tool for research in cancer biology and lipid metabolism.
Enniatin A1 is a cyclic hexadepsipeptide that functions as an apoptosis inducer. Isolated from Fusarium mycotoxins, this compound exhibits anticarcinogenic properties primarily through the induction of apoptosis and disruption of the ERK signaling pathway. In addition, Enniatin A1 demonstrates inhibitory activity against acyl-CoA:cholesterol acyltransferase (ACAT) with an IC50 of 49 μM in rat liver microsomes, making it a valuable tool for research in cancer biology and lipid metabolism.
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