Epertinib hydrochloride

Catalog No.: A21950

EGFR, HER2 and HER4 inhibitor

Epertinib hydrochloride

Epertinib hydrochloride Chemical Structure

CAS NO. 2071195-74-7

Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively. Epertinib shows potent antitumor activity.

Availability: In stock

Package Price Qty
5 mg
$315.00
10 mg
$543.00
50 mg
$1,610.00
100 mg
$3,220.00
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Biological Activity

Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively. Epertinib shows potent antitumor activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.77 mL 83.83 mL 167.65 mL
0.5 mM 3.35 mL 16.77 mL 33.53 mL
1 mM 1.68 mL 8.38 mL 16.77 mL
5 mM 0.34 mL 1.68 mL 3.35 mL

*The above data is based on the productmolecular weight 596.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A21950
Actions Inhibitor
M. Wt 596.48
Formula C30H28Cl2FN5O3
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2071195-74-7
Synonyms S-22611 hydrochloride, S22611, S 22611
SMILES CC#C/C(C1=CC2=C(NC3=CC=C(OCC4=CC=CC(F)=C4)C(Cl)=C3)N=CN=C2C=C1)=N\OC[[email protected]@H]5NCCOC5.Cl

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