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$0.00 Biological Activity
Epertinib hydrochloride is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4, with IC50s of 1.48 nM, 7.15 nM and 2.49 nM, respectively. Epertinib shows potent antitumor activity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.77 mL | 83.83 mL | 167.65 mL |
| 0.5 mM | 3.35 mL | 16.77 mL | 33.53 mL |
| 1 mM | 1.68 mL | 8.38 mL | 16.77 mL |
| 5 mM | 0.34 mL | 1.68 mL | 3.35 mL |
*The above data is based on the productmolecular weight 596.48. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21950 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 596.48 |
| Formula | C30H28Cl2FN5O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 2071195-74-7 |
| Synonyms | S-22611 hydrochloride, S22611, S 22611 |
| SMILES | CC#C/C(C1=CC2=C(NC3=CC=C(OCC4=CC=CC(F)=C4)C(Cl)=C3)N=CN=C2C=C1)=N\OC[[email protected]@H]5NCCOC5.Cl |
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