Epiallopregnanolone

Catalog No.: A66696
GABAA Receptor Antagonist
Epiallopregnanolone (5α,3β-THDOC) is a neurosteroid that acts as an antagonist at GABAA receptors while enhancing NMDA receptor activity. This compound plays a significant role in modulating neurotransmission and has potential applications in neuropharmacology research, particularly in studies exploring anxiety, depression, and neurodegenerative disorders. Its unique mechanism of action makes it a valuable tool for understanding the complexities of synaptic transmission and receptor interactions in the central nervous system.
Grouped product items
Size Price Stock Qty
1mg
$50.00
In stock
5mg
$125.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEpiallopregnanolone (5α,3β-THDOC) is a neurosteroid that acts as an antagonist at GABAA receptors while enhancing NMDA receptor activity. This compound plays a significant role in modulating neurotransmission and has potential applications in neuropharmacology research, particularly in studies exploring anxiety, depression, and neurodegenerative disorders. Its unique mechanism of action makes it a valuable tool for understanding the complexities of synaptic transmission and receptor interactions in the central nervous system.
Product Information
Catalog NumA66696
FormulaC21H34O3
Molecular Weight334.49
CAS Number567-01-1
SMILESC[C@]12[C@]([H])([C@@]3(CC[C@]4(C[C@H](CC[C@@]4([C@]3(CC2)[H])C)O)[H])[H])CC[C@@H]1C(CO)=O
Synonyms5α,3β-THDOC
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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