Epirubicin HCl

Catalog No.: A10345

Topoisomerase II inhibitor

Epirubicin HCl Chemical Structure

CAS NO. 56390-09-1

Epirubicin is a cell-permeable anthracycline antitumor antibiotic. It is a stereoisomer(4′-epi-isomer) of doxorubicin that exhibits reduced cardiotoxicity. It is used to inhibit topoisomerase II and DNA helicase activity.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $40.00

Special Price $32.00

10 mg

Regular Price: $70.00

Special Price $56.00

50 mg

Regular Price: $200.00

Special Price $160.00

100 mg

Regular Price: $320.00

Special Price $256.00

10mM * 1mL in DMSO
$60.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

Epirubicin is a cell-permeable anthracycline antitumor antibiotic. It is a stereoisomer(4′-epi-isomer) of doxorubicin that exhibits reduced cardiotoxicity. It is used to inhibit topoisomerase II and DNA helicase activity.
Targets
Topoisomerase (Cell-free assay)
In vitro DMSO 100 mg/mL (172.41 mM)
Water 100 mg/mL heating (172.41 mM)
Ethanol <1 mg/mL (<1 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 17.24 mL 86.21 mL 172.41 mL
0.5 mM 3.45 mL 17.24 mL 34.48 mL
1 mM 1.72 mL 8.62 mL 17.24 mL
5 mM 0.34 mL 1.72 mL 3.45 mL

*The above data is based on the productmolecular weight 580. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10345
Actions Inhibitor
M. Wt 580
Formula C27H30ClNO11
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 56390-09-1
Synonyms Ellence, Pharmorubicin, Epirubicin Ebewe
SMILES C[[email protected]]1[[email protected]@H]([[email protected]](C[[email protected]@H](O1)O[[email protected]]2C[[email protected]@](CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)O.Cl

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