EPZ-5676 (Pinometostat)

EPZ-5676 is a small molecule inhibitor of histone methyltransferase with potential antineoplastic activity.
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Product Name Price Stock Qty
EPZ-5676 5mg
In stock
EPZ-5676 10mg
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EPZ-5676 25mg
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EPZ-5676 50mg
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EPZ-5676 10mM * 1mL in DMSO
In stock

Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's EPZ-5676 (Pinometostat) has been cited by 2 publications
  • Yoo H, .et al. , Cell Death Dis, 2020, Jan; 11(1): 14 PMID: 31908356
  • Guang Bai, .et al. , Epigenetics of Chronic Pain, 2019, Pages 1-48
  • Biological Activity
    Discription EPZ-5676 is a small molecule inhibitor of histone methyltransferase with potential antineoplastic activity.
    Target Value
    Chemical Information
    Catalog Num A12735
    Formula C30H42N8O3
    Molecular Weight 562.7
    CAS Number 1380288-87-8
    SMILES CC(C)N(C[C@@H]1[C@H]([C@H]([C@@H](O1)N2C=NC3=C2N=CN=C3N)O)O)C4CC(C4)CCC5=NC6=C(N5)C=C(C=C6)C(C)(C)C
    Synonyms EPZ5676, EPZ 5676

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    In vitro (25°C) DMSO Warmed: 88 mg/mL (156.38 mM)
    Water Insoluble
    Ethanol Warmed: 81 mg/mL (143.94 mM)
    In vivo 2% DMSO+30% PEG 300+5% Tween 80+ddH2O 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 17.77 mL 88.86 mL 177.71 mL
    0.5 mM 3.55 mL 17.77 mL 35.54 mL
    1 mM 1.78 mL 8.89 mL 17.77 mL
    5 mM 0.36 mL 1.78 mL 3.55 mL
    Useful Calculator

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    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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