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Publications citing Adooq Products
EPZ-5676 (Pinometostat) Citations (1)
- Guang Bai, .et al. Chapter 1 - Epigenetic Tools in Chronic Pain Studies, Epigenetics of Chronic Pain, 2019, Pages 1-48
Chemical Information
| Catalog Num | A12735 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 562.7 |
| Formula | C30H42N8O3 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 1380288-87-8 |
| Synonyms | EPZ5676, EPZ 5676 |
| SMILES | CC(C)N(C[[email protected]@H]1[[email protected]]([[email protected]]([[email protected]@H](O1)N2C=NC3=C2N=CN=C3N)O)O)C4CC(C4)CCC5=NC6=C(N5)C=C(C=C6)C(C)(C)C |
Description |
EPZ-5676 is a small molecule inhibitor of histone methyltransferase with potential antineoplastic activity. | ||||||||||
Targets |
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| Solubility (25°C) * | In vitro | DMSO | 100 mg/mL (177.71 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | 100 mg/mL (177.71 mM) | ||
| In vivo | 30% PEG400/0.5% Tween80/5% propylene glycol | 30 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.77 mL | 88.86 mL | 177.71mL |
| 0.5 mM | 3.55 mL | 17.77 mL | 35.54 mL |
| 1 mM | 1.78 mL | 8.89 mL | 17.77 mL |
| 5 mM | 0.36 mL | 1.78 mL | 3.55 mL |
*The above data is based on the productmolecular weight 562.7. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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