ER-38925 is a selective retinoid agonist targeting retinoic acid receptor subtype α (RAR-α). This compound demonstrates a dose-dependent ability to prolong the lifespan of recipient mice and effectively inhibits alloantigen-stimulated donor T lymphocyte proliferation in vitro. Additionally, ER-38925 can prevent the development of antiallogeneic cytotoxic T lymphocyte responses and suppress serum anti-DNA autoantibody production in mouse models of human chronic graft-versus-host disease (GVHD). Its unique properties make it a valuable tool for research in immunological responses and therapy development.
ER-38925 is a selective retinoid agonist targeting retinoic acid receptor subtype α (RAR-α). This compound demonstrates a dose-dependent ability to prolong the lifespan of recipient mice and effectively inhibits alloantigen-stimulated donor T lymphocyte proliferation in vitro. Additionally, ER-38925 can prevent the development of antiallogeneic cytotoxic T lymphocyte responses and suppress serum anti-DNA autoantibody production in mouse models of human chronic graft-versus-host disease (GVHD). Its unique properties make it a valuable tool for research in immunological responses and therapy development.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
