ERRγ-IN-1 is a potent ERRγ inhibitor with an IC50 of 0.040 μM. It demonstrates activation of the MAPK (p44/p42) pathway while effectively inhibiting ERRγ activity. ERRγ-IN-1 has been shown to enhance iodine uptake in anaplastic thyroid carcinoma xenografts and to suppress tumor growth in nude mouse models. This compound is valuable for research focused on anaplastic thyroid carcinoma.
ERRγ-IN-1 is a potent ERRγ inhibitor with an IC50 of 0.040 μM. It demonstrates activation of the MAPK (p44/p42) pathway while effectively inhibiting ERRγ activity. ERRγ-IN-1 has been shown to enhance iodine uptake in anaplastic thyroid carcinoma xenografts and to suppress tumor growth in nude mouse models. This compound is valuable for research focused on anaplastic thyroid carcinoma.
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