ErSO-DFP is an anticipatory unfolded protein response (a-UPR) activator with enhanced selectivity for estrogen receptor alpha-positive (ERα+) cancer cells, exhibiting a broader selectivity profile compared to its predecessor, ErSO. This compound demonstrates significant antitumor activity against MCF-7 cancer models in murine studies. Additionally, ErSO-DFP is capable of crossing the blood-brain barrier, making it a valuable tool for research in cancer therapeutics and neuro-oncology applications.
ErSO-DFP is an anticipatory unfolded protein response (a-UPR) activator with enhanced selectivity for estrogen receptor alpha-positive (ERα+) cancer cells, exhibiting a broader selectivity profile compared to its predecessor, ErSO. This compound demonstrates significant antitumor activity against MCF-7 cancer models in murine studies. Additionally, ErSO-DFP is capable of crossing the blood-brain barrier, making it a valuable tool for research in cancer therapeutics and neuro-oncology applications.
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