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Esculentoside L

Catalog No.: B18804
Anticancer Agent
Esculentoside L is a triterpene saponin derived from the roots of Phytolacca americana, targeting multidrug-resistant cancer cells. It enhances the intracellular accumulation of calcein in human ovarian cancer cells, making it a promising candidate for overcoming drug resistance in cancer therapy. Esculentoside L exhibits minimal cytotoxic effects on non-cancerous cells and hepatocytes, supporting its potential use in targeted research applications related to multidrug-resistant human ovarian cancer.
Esculentoside L 130364-33-9 Anticancer Agent
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEsculentoside L is a triterpene saponin derived from the roots of Phytolacca americana, targeting multidrug-resistant cancer cells. It enhances the intracellular accumulation of calcein in human ovarian cancer cells, making it a promising candidate for overcoming drug resistance in cancer therapy. Esculentoside L exhibits minimal cytotoxic effects on non-cancerous cells and hepatocytes, supporting its potential use in targeted research applications related to multidrug-resistant human ovarian cancer.
Product Information
Catalog NumB18804
FormulaC48H76O20
Molecular Weight973.11
CAS Number130364-33-9
SMILESC[C@@]1(C(OC)=O)CC[C@]2(C(O[C@H]3[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O3)=O)CC[C@]4(C)C([C@H]2C1)=CC[C@H]5[C@@]4(C)CCC6[C@]5(C)CC[C@H](O[C@H]7[C@H](O)[C@@H](O)[C@H](O[C@H]8[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O8)CO7)[C@]6(CO)C
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