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Biological Activity
Esomeprazole sodium is a proton pump inhibitor which reduces acid secretion through inhibition of the H+ / K+ ATPase in gastric parietal cells.
Targets
| ATPase | ||||
| In vitro | DMSO | 72 mg/mL (195.97 mM) | |
| Water | 72 mg/mL (195.97 mM) | ||
| Ethanol | 72 mg/mL (195.97 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.22 mL | 136.09 mL | 272.18 mL |
| 0.5 mM | 5.44 mL | 27.22 mL | 54.44 mL |
| 1 mM | 2.72 mL | 13.61 mL | 27.22 mL |
| 5 mM | 0.54 mL | 2.72 mL | 5.44 mL |
*The above data is based on the productmolecular weight 367.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A10365 |
|---|---|
| Actions | Inhibitor |
| CAS No. | 161796-78-7 |
| Formula | C17H18N3NaO3S |
| M. Wt | 367.4 |
| Purity | >98% |
| Synonyms | (S)-Omeprazole sodium |
| SMILES | CC1=CN=C(C(=C1OC)C)CS(=O)C2=NC3=C([N-]2)C=C(C=C3)OC.[Na+] |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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