Estriol is an orally active estrogen that acts as an agonist of estrogen receptors ERα and ERβ. It exhibits antagonistic activity against GPR30 in estrogen receptor-negative breast cancer cells, making it a valuable compound in cancer research. Additionally, Estriol has been shown to mitigate disease severity via immunomodulatory mechanisms that reduce tissue inflammation, while also demonstrating proconvulsant properties. Its diverse biological activities make it relevant for studies on hormone-related disorders and cancer therapeutics.
Estriol is an orally active estrogen that acts as an agonist of estrogen receptors ERα and ERβ. It exhibits antagonistic activity against GPR30 in estrogen receptor-negative breast cancer cells, making it a valuable compound in cancer research. Additionally, Estriol has been shown to mitigate disease severity via immunomodulatory mechanisms that reduce tissue inflammation, while also demonstrating proconvulsant properties. Its diverse biological activities make it relevant for studies on hormone-related disorders and cancer therapeutics.
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