Estrogen receptor α antagonist 1

Catalog No.: A85231
Estrogen Receptor α Antagonis
Estrogen Receptor α Antagonist 1 is a highly selective antagonist specifically targeting the estrogen receptor α (ERα), displaying IC50 values of 0.02 μM for ERα, 6.55 μM for estrogen receptor β, and 7.73 μM for MCF-7 cells. This compound offers significant potential for research applications in cancer biology, particularly in studies focusing on estrogen signaling pathways and their involvement in malignancies. Its selectivity makes it a valuable tool for investigating the role of ERα in cancer progression and therapy.
Grouped product items
Size Price Stock Qty
25mg
$1,800.00
In stock
50mg
$2,285.00
In stock
100mg
$2,815.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionEstrogen Receptor α Antagonist 1 is a highly selective antagonist specifically targeting the estrogen receptor α (ERα), displaying IC50 values of 0.02 μM for ERα, 6.55 μM for estrogen receptor β, and 7.73 μM for MCF-7 cells. This compound offers significant potential for research applications in cancer biology, particularly in studies focusing on estrogen signaling pathways and their involvement in malignancies. Its selectivity makes it a valuable tool for investigating the role of ERα in cancer progression and therapy.
Product Information
Catalog NumA85231
FormulaC26H32N2O5
Molecular Weight452.54
CAS Number2580941-45-1
SMILESO=C(C1=C(N)OC2=C(C=CC(O)=C2)C1C3=CC=C(OCCN4CCCC4)C=C3)OCCCC
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C1V1 = C2V2

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