Biological Activity
ETC-159 is a potent and specific inhibitor of Wnt secretion. ETC-159 inhibits beta-catenin reporter activity in a dose-dependent manner with an IC50 of 2.9 nM.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 25.55 mL | 127.75 mL | 255.51 mL |
0.5 mM | 5.11 mL | 25.55 mL | 51.1 mL |
1 mM | 2.56 mL | 12.78 mL | 25.55 mL |
5 mM | 0.51 mL | 2.56 mL | 5.11 mL |
*The above data is based on the productmolecular weight 391.38. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A15840 |
---|---|
Actions | Inhibitor |
M. Wt | 391.38 |
Formula | C19H17N7O3 |
Solubility | DMSO |
Purity | >98% |
Storage | at -20°C 3 years Powder |
CAS No. | 1638250-96-0 |
Synonyms | ETC-1922159 |
SMILES | O=C1C2C(N=CN2C(CNC3=CC=C(C4=CC=CC=C4)N=N3)=O)N(C)C(N1C)=O |
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