EUK-134 is a synthetic superoxide dismutase (SOD) mimetic with catalase activity, primarily targeting oxidative stress in cellular environments. This compound exhibits mitoprotective antioxidant properties, effectively reducing ischemia-reperfusion-induced damage in rat kidneys. In H9C2 cardiac cells, EUK-134 decreases the expression levels of NF-κB, malondialdehyde (MDA), and protein carbonylation, making it a valuable tool for research on oxidative stress and cellular protection mechanisms.
EUK-134 is a synthetic superoxide dismutase (SOD) mimetic with catalase activity, primarily targeting oxidative stress in cellular environments. This compound exhibits mitoprotective antioxidant properties, effectively reducing ischemia-reperfusion-induced damage in rat kidneys. In H9C2 cardiac cells, EUK-134 decreases the expression levels of NF-κB, malondialdehyde (MDA), and protein carbonylation, making it a valuable tool for research on oxidative stress and cellular protection mechanisms.
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