EZH2-IN-21 is a potent inhibitor of the histone lysine methyltransferase enhancer of zeste homologue 2 (EZH2), demonstrating significant anticancer activity. It acts competitively with the cofactor S-adenosylmethionine (SAM) and non-competitively with peptide or nucleosome substrates. This compound is instrumental in research applications focused on targeted cancer therapies and understanding the epigenetic regulation of gene expression.
EZH2-IN-21 is a potent inhibitor of the histone lysine methyltransferase enhancer of zeste homologue 2 (EZH2), demonstrating significant anticancer activity. It acts competitively with the cofactor S-adenosylmethionine (SAM) and non-competitively with peptide or nucleosome substrates. This compound is instrumental in research applications focused on targeted cancer therapies and understanding the epigenetic regulation of gene expression.
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