FAAH-IN-5 is an irreversible inhibitor of fatty acid amide hydrolase (FAAH) with a reported IC50 of 10.5 nM, demonstrating relative selectivity. This compound is suitable for research applications focused on endocannabinoid signaling pathways and pain modulation. Despite its potency, FAAH-IN-5 exhibits low permeability in the Parallel Artificial Membrane Permeability Assay (PAMPA), making it an important tool for studies in pharmacokinetics and bioavailability.
FAAH-IN-5 is an irreversible inhibitor of fatty acid amide hydrolase (FAAH) with a reported IC50 of 10.5 nM, demonstrating relative selectivity. This compound is suitable for research applications focused on endocannabinoid signaling pathways and pain modulation. Despite its potency, FAAH-IN-5 exhibits low permeability in the Parallel Artificial Membrane Permeability Assay (PAMPA), making it an important tool for studies in pharmacokinetics and bioavailability.
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