FAAH-IN-6 is a potent fatty acid amide hydrolase (FAAH) inhibitor that effectively crosses the blood-brain barrier, exhibiting IC50 values of 0.72 nM and 0.28 nM for human and rat FAAH, respectively. This compound demonstrates significant dose-dependent analgesic effects in preclinical models of neuropathic and inflammatory pain, making it valuable for research on pain management and therapeutic interventions targeting the endocannabinoid system.
FAAH-IN-6 is a potent fatty acid amide hydrolase (FAAH) inhibitor that effectively crosses the blood-brain barrier, exhibiting IC50 values of 0.72 nM and 0.28 nM for human and rat FAAH, respectively. This compound demonstrates significant dose-dependent analgesic effects in preclinical models of neuropathic and inflammatory pain, making it valuable for research on pain management and therapeutic interventions targeting the endocannabinoid system.
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